© 2023 Interventional Psychiatry of Arizona. All Rights Reserved.
Spravato is the first prescription nasal spray, taken with an oral antidepressant.
It works similarly to ketamine and is best for:
SPRAVATO® (esketamine) CIII nasal spray is a non-selective, non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor – an ionotropic glutamate receptor. It is a first-of-its kind medicine approved by the FDA in two major depressive disorder (MDD) subpopulations with high unmet need.
SPRAVATO® is approved in the United States, in conjunction with an oral antidepressant to treat adults with treatment-resistant depression (TRD) and to treat depressive symptoms in adults with MDD with acute suicidal ideation or behavior.
SPRAVATO® is a prescription medicine, used along with an antidepressant taken by mouth to treat:
SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic).
We are now Risk Evaluation and Mitigation Strategy (REMS)-certified to provide SPRAVATO® (esketamine) CIII, a nasal spray approved for use, in conjunction with an oral antidepressant, to treat depressive symptoms in adults with MDD with acute suicidal ideation or behavior.
Our medical staff are trained to prescribe, dispense and administer SPRAVATO®, and we have established processes and procedures in accordance with the REMS. A healthcare provider will provide direct supervision as the patient self-administers SPRAVATO® and will monitor every patient after every dose for at least two hours for resolution of sedation and dissociation and changes in vital signs. SPRAVATO® must never be dispensed directly to a patient for home use.
Additionally, all patients require transportation from our clinic following the observation period, as they should not drive or operate machinery until the day after a treatment session, following a restful sleep.
The use of Spravato with medications has been shown to produce significant reduction of depressive symptoms as quickly as 24 hours.
If you continue to experience significant depressive symptoms despite having tried two or more antidepressants and/or with therapy, talk to our psychiatrist about Spravato.
Most Common Side Effects:
If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.
Do not take if you have a history of: